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Citrus plants are of great interest because they
2020-01-15

Citrus plants are of great interest because they contain large amounts of flavonoids, and citrus fruits and their juices are consumed in large quantities around the world [18]. The flavonoid contents and profiles of citrus juices vary greatly with the type of fruit. It has been determined that citru
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Following the relationship model adopted in this work
2020-01-15

Following [20], [22], the relationship model adopted in this 4E1RCat work to estimate the time to failure is the Inverse Power Law (IPL): Where L is the SUT life characteristic (e.g. the mean time to failure), s represents the stress level, while k and w are model-related parameters to be defined fr
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Due to its several industrial applications the recombinant p
2020-01-15

Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian Tianeptine sodium synthesis (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms (Tom
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Another potential source of variable affinities
2020-01-15

Another potential source of variable affinities is inherent in the method of RBA determination. While several reports simply use relative IC50 values as RBAs [11], [12], [13], [14], [15], these are only an approximate measure of relative affinity since IC50 varies due to experimental and biological
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We have previously characterized the
2020-01-14

We have previously characterized the leucine-rich NESs located within the zinc-binding domains of mucosal high risk HPV16 E7 (76IRTLEDLLM84) and low risk HPV11 E7 (76IRQLQDLLL84) mediating their nuclear export in a CRM1 dependent manner (Knapp et al., 2009, McKee et al., 2013). The zinc-binding doma
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CRF and urocortin I are not only readily found throughout
2020-01-14

CRF and urocortin I are not only readily found throughout the spinal cord (Korosi et al., 2007), CRF analogs are clearly able to alter nociceptive signals (Imbe et al., 2010; Lariviere and Melzack, 2000). However, it was unclear whether they are released endogenously and involved in the spinal modul
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It should be noted that there are other methods such
2020-01-14

It should be noted that there are other methods, such as artificial intelligence, like Artificial Neural Networks/ANN (such as PSO-ANN, ICA-ANN), Least Square Support Vector Machine/LSSVM, etc. [10], [11], [12], [13], [14], [15], [16], [17], [18], or molecular simulations, for modeling the fluid\'s
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br Materials and methods br Results br
2020-01-14

Materials and methods Results Discussion In particular, we showed that pancreatic neuroendocrine tumor began to recognize cAMP as a stimulatory signal for cell proliferation. Conversely, cAMP was found to have an inhibitory effect on cell proliferation in bronchial carcinoids cells. The di
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the black and white film In the present study we found
2020-01-14

In the present study, we found that the up-regulatory effects of androgens on ep1 transcripts might be mediated by Arα in the olfactory rosette of B. sinensis. However, in mammals, there is no evidence of AR expression in either the vomeronasal organ or the sensory epithelium of main olfactory epith
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OHC is a potent regulator of LXR mediated pathways that
2020-01-14

25-OHC is a potent regulator of LXR-mediated pathways, that impact on 5,8,11-Eicosatriynoic Acid lipid homeostasis [8]. This oxysterol affects expression of the cholesterol efflux pumps ATP-binding cassette transporter (ABC)A1 [9] and ABCG1, and expression of apolipoprotein E [10], [11], [12]. 25-O
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HCV has evolved mechanisms to evade humoral
2020-01-14

HCV has evolved mechanisms to evade humoral immune responses including high functional flexibility and variability of immunogenic portions of its envelope proteins. The highest sequence variability occurs in the first 27 Caspase-9 Colorimetric Assay Kit of the N-terminus of E2, which is referred to
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Salinosporamide A receptor The use of inhibitors clearly has
2020-01-14

The use of inhibitors clearly has its caveats and the field should come to a consensus on etomoxir concentration to maximally block LC-FAO while minimalizing off-target effects. The current papers convincingly show that 200 μM is too high, but it should be noted that 3 μM does not fully suppress LC-
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Previous studies have documented that SCFAs may elicit
2020-01-14

Previous studies have documented that SCFAs may elicit effects on lipid metabolism via de novo synthesis and transport. Acetate is not only used as an energy source, but is also constituted as a substrate for the cholesterol synthesis in the liver through acetyl-CoA, thus affecting plasma cholestero
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br Methods br Discussion In a recent survey among high
2020-01-14

Methods Discussion In a recent survey among 2625 high risk patients on atorvastatin, 10.5% of patients achieved an LDL-target of (+)-Bicuculline australia level for improvement of acceptance and adherence to effective lipid lowering therapy are warranted to maximize the benefits of standard t
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Key molecules in the EP second messenger signaling cascade t
2020-01-14

Key molecules in the EP1 second messenger signaling cascade that are necessary for potentiation of GluK2/GluK5 were identified. We also identified three GluK5 serines located in a membrane-proximal C-terminal domain that, when mutated to the phosphomimetic aspartate and expressed with GluK2, rendere
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