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In the belief that DNA
2020-01-02
In the belief that DNA-based nanosensors and DNA microarrays should be easier to operate, faster, more accurate and more economically viable than PCR-based techniques, an electrochemical DNA biosensor was designed for detection of G. boninense[9], [10]. This was developed based on a gold electrode m
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CAA is a carcinogenic metabolite
2020-01-02
CAA is a carcinogenic metabolite of vinyl chloride, forming several different DNA adducts including the cyclic kinesin spindle protein adducts 3,N4-ethenocytosine (εC), 1,N6-ethenoadenine (εA), N2,3-ethenoguanine (εG), and 1,N2-ethenoguanine (1,N2-εG), with the A and C cyclic adducts the most predo
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br Materials and methods br Results br
2020-01-02
Materials and methods Results Discussion The first DGAT1 gene was described in the mouse in 1998 [28], and a few years later DGAT2 was identified from the oleaginous fungus Mortierella ramanniana[29]. Although both of them are known as the primary enzymes for de novo TAG biosynthesis, they
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In general up to date no study has
2020-01-02
In general, up to date, no study has considered thermodynamic modeling to estimate the PHA-848125 of SO2 by different DESs. Since experimental measurements are time consuming and expensive, general and accurate theoretical models are vital to estimate SO2 solubilities in different DESs over wide ra
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(+)-Bicuculline Second when considering the Poisson point pr
2020-01-02
Second, when considering the Poisson point process, the high-density or large-radius limit of the percolation probability tends to 1 exponentially fast and is governed by the isolation probability. In the random environment, the picture is more subtle since the regime of a large radius is no longer
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Our results on the acute effects of
2020-01-02
Our results on the acute effects of THC on resting state NNC 55-0396 australia function are in line with previous neuroimaging findings. Increased perfusion after THC administration in insular and prefrontal regions has previously been reported in smaller samples (Mathew et al., 1997, Mathew et al.
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br Materials and methods br Results
2019-12-31
Materials and methods Results Artemis has been reported to possess 5′–3′ exonuclease activity in vitro on ssDNA, as well as DNA-PK-dependent endonuclease activity on single-strand overhang and hairpin DNA structures [11]. However, enzymes within the metallo-β-lactamase family typically contain
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Expression of MGMT in human cells
2019-12-31
Expression of MGMT in human Clofarabine australia can be switched off by enzymatic methylation of a cytosine residue in the MGMT promoter sequence. In this regard, both MGMT and the mismatch repair function MLH1 belong to a subset of DNA repair genes that are subjected to epigenetic control. In cons
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Moreover maintaining the pyrimidine pool is not the only
2019-12-31
Moreover, maintaining the pyrimidine pool is not the only important role played by DHODHs. In Toxoplasma gondii, for instance, DHODH plays a second essential function [38] possibly coupled to the mitochondrial respiratory activity, where it replenishes ubiquinol levels and prevents reactive oxygen s
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Almost all previously published haplotype association studie
2019-12-31
Almost all previously published haplotype association studies have demonstrated the importance of haplotype reconstruction because the combinations of SNPs exert synergistic effects on protein function. Even synonymous polymorphisms within haplotypes can have functional consequences that are drastic
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As mentioned above of various constitutive models the
2019-12-31
As mentioned above, of various constitutive models, the Chaboche kinematic model was widely used [3,7,[23], [24], [25], [26], [27]]. There exist many significant literature around the Chaboche/Chaboche type plasticity model calibration and its parameter determination methods. Aguis et al. [28] emplo
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Progesterone s metabolite THP may also be mediating
2019-12-31
Progesterone\'s metabolite, 3α,5α-THP, may also be mediating burying and freezing responses. Results show female Long–Evans rats in behavioral estrous have higher P4 levels in serum, NVP-LCQ195 and hippocampus compared to diestrous female Long–Evans rats. Additionally, ovx female Long–Evans rat adm
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The Ewing sarcoma breakpoint region gene EWSR is
2019-12-31
The Ewing sarcoma breakpoint region 1 gene (EWSR1) is a partner in a large, diverse range of mesenchymal (and some nonmesenchymal) tumors (Tables 1 and 2). As the 5′ partner, EWSR1 is able to fuse with an array of genes. These fusions can generate genetically different but phenotypically identical n
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A phenylacetic acid derivative discovered in a
2019-12-30
A phenylacetic Myelin Basic Protein (87-99) australia derivative (), discovered in a high throughput screen for CRTH2, inhibited the binding of H-PGD to CRTH2 receptors on 293 cells with an IC of 0.010μM, and inhibited the binding of H-PGD to DP receptors with an IC of only 8.3μM (). Compound als
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br Conclusion In this study
2019-12-30
Conclusion In this study, we have shown the construction, expression and purification of CPG2 fused to the HIV-1 TAT peptide (TAT–CPG2). We have demonstrated for the first time that TAT-CPG2 in both native and denatured forms could be efficiently transduced into the HepG2 cells. Also, we have pro
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