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Secondary and primary studies have considered the decision t
2020-06-12
Secondary and primary studies have considered the decision to select the provider and to select components after the component origin is chosen. Examples of secondary and primary studies outside our scope, but still related to decision-making are listed in Tables 1 and 2. The secondary and primary s
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br Introduction Concrete is one of
2020-06-12
Introduction Concrete is one of the most commonly used materials in the construction industry and its raw material is available throughout the world. Concrete is derived from ordinary Portland cement and is used for the construction and development of infrastructures. Research shows that demand f
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br Conflicts of interest br Author contributions br Acknowle
2020-06-12
Conflicts of interest Author contributions Acknowledgements This work was supported by the University of Brescia (ex 60%) and Siderurgica Leonessa research funds to AF. RR was supported by Associazione Italiana per la Ricerca sul Cancro - AIRC (MFAG 18459 grant). We are grateful to Umberto
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It is well known that the tumor
2020-06-12
It is well known that the tumor suppressor p53 plays an important role in regulating the Sennoside A and cellular senescence [43,46,48]. For example, FOXO4 could interact with P53, which selectively induced apoptosis in senescent cells [48]. In addition, loss of MECP2 was found to lead to the induc
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Materials and methods br Results
2020-06-12
Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino Dioscin synthesis for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity with the e
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In contrast to AChE BuChE Table exhibited
2020-06-12
In contrast to AChE, BuChE (Table 2) exhibited a measurable time-dependent inactivation only with Phosphoramidon Disodium Salt 2 among the four acetophenones in this study. Values of Ki obtained from steady-state inhibition of BuChE by all four acetophenones were, as noted in the Results, 10- to 20
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br Experimental br Results br Discussion In the last
2020-06-12
Experimental Results Discussion In the last two decades, several studies have shown an important role for progestogens, and in particular ALLO, in the modulation of Schwann cell physiology, regulating several biochemical and functional parameters. The classical PR has been found both in rat
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br Experimental br Results and discussion br
2020-06-11
Experimental Results and discussion Conclusions In this work we presented the direct electrochemical behaviour of the Mo containing formate dehydrogenase, purified from D. desulfuricans, where the Mo centre redox features were observed. The results allowed to calculate the reduction potenti
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Furthermore our sample preparation uses a simple
2020-06-11
Furthermore, our sample preparation uses a simple isolation procedure. Numerous CYP450 phenotyping methods employed extensive extraction procedures for sample preparation such as dual liquid extraction or solid phase extraction which are costly and time consuming [10], [17], [18], [19], [20], [23],
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Thienoguanosine Targeting a specific cell type rather than t
2020-06-11
Targeting a specific cell type, rather than the broad cytotoxicity exhibited by some of the pharmacological agents currently used to treat lupus, may improve efficacy and decrease off target toxicity. Thus, evidence that macrophages and microglia are important to the pathogenesis of LN and NPSLE, re
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Further proof is required as to whether ER membrane receptor
2020-06-11
Further proof is required as to whether ER membrane receptors play a role in the maintenance of bone mass. It is also possible that other non-genomic pathways may be involved. Nevertheless, whatever the precise mechanism of action of estrogens may be, the imbalance between bone formation and resorpt
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br Materials and methods br Results and discussion
2020-06-11
Materials and methods Results and discussion Conclusions The fabrication and characterization of AMCs reinforced with SiC and RHA was done in this study. Following conclusions are drawn from the above study: Conflict of interest Authors\' contributions Introduction Industrialisati
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Despite many studies having demonstrated the importance of c
2020-06-11
Despite many studies having demonstrated the importance of connexin43 (Cx43), the most abundant connexin in bone cells, for bone development and turnover during the last decade [27], little is currently known about GJIC and Cx43 in primary bone tumors. In this report, we analyzed the specific role o
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This relative lack of ET expression in highly malignant epit
2020-06-11
This relative lack of ET-1 expression in highly malignant epithelial CRT0044876 could be explained by marked cellular anaplasia and cellular dysfunction; we also suggest that the high levels of VEGF, which have been evidenced in highly malignant mammary tumours (Restucci et al., 2002) may suppress E
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A range of inhibitors were therefore synthesized
2020-06-11
A range of inhibitors were therefore synthesized containing either carboxylic Cy3.5 maleimide or ester functionality at the ‘tail’ group as well as variations in the ‘head.’ These were assayed in vitro using the DCIP assay for binding affinity against and human DHODH at 50μM, respectively (). Analy
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